Injectable Peptide Therapy: A Primer for Orthopaedic and Sports Medicine Physicians

As injectable peptide therapies become increasingly prevalent in sports medicine, this primer by Mayfield, Bolia, Feingold, and colleagues provides orthopaedic and sports medicine physicians with a foundational understanding of these emerging treatments. Published in The American Journal of Sports Medicine, the study addresses a critical knowledge gap for clinicians seeking evidence-based guidance on peptide use.

The authors systematically reviewed the available literature on injectable peptide therapies relevant to sports medicine, covering mechanisms of action, clinical indications, dosing considerations, and safety profiles. Their goal was to create a practical resource for physicians encountering peptide therapies in their practice.

The review validated the growing clinical adoption of injectable peptides for tissue repair and performance recovery. Peptides such as ipamorelin and other growth hormone secretagogues showed particular promise for supporting musculoskeletal healing, reducing recovery times, and helping athletes return to activity more quickly.

This primer represents an important step in bridging the gap between peptide research and clinical practice. For sports medicine physicians, having a comprehensive reference for injectable peptide therapies means better-informed treatment decisions and improved outcomes for patients recovering from sports-related injuries.